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Washington and Lee University

Washington and Lee University

Natalia Toporikova

Assistant Professor of Biology

Howe Hall


Ph.D. - Florida State University, Tallahassee, FL
Postdoctoral Fellow - McGill University, Montreal, QC
Postdoctoral Fellow - Georgia Institute of Technology, Atlanta, GA


I am applying methods of computational modeling to study a wide range of biological systems. Some recent projects include neural control of breathing, pregnancy initiation in rats and signal detection by electric fish.


Dynamics of Biological systems (Biology 282)

Selected Publications

  1. Toporikova N., Butera R. Two modalities of bursting in inspiratory pacemakers: an integrative model J Comput. Neurosci., 2011 Jun;30(3):515-28.
  2. Toporikova N., Chacron M. SK channels gate information processing in vivo by regulating an intrinsic bursting mechanism seen in vitro. J Neurophysiol., 2009 Oct;102(4):2273-87.
  3. Toporikova N., Tabak J., Freeman M. E., Bertram R. A-type K+ current can act as a trigger for bursting in the absence of a slow variable. Neural Computation, 2008, 20(2).
  4. Tabak J., Toporikova N., Freeman M. E., Bertram R. Low dose of dopamine may stimulate prolactin secretion by increasing fast potassium currents. J. Comput. Neurosci., 2007 Apr;22(2):211-22.
  5. Bertram R., Tabak J., Toporikova N., Freeman M. E. Endothelin action on pituitary lactotrophs: one receptor, many GTP-binding proteins. Science STKE, 2006 Jan 24; (319):pe4, Review.
  6. Bertram R., Egli M., Toporikova N., Freeman M. E. A mathematical model for the mating-induced prolactin rhythm of female rats. Am. J. Physiol. Endocrinol. Metab., 2006 Mar; 290(3):E573-82.
  7.  Egli M., Bertram R., Toporikova N., Sellix M. T., Blanco W., Freeman M. E. Prolactin secretory rhythm of mated rats induced by a single injection of oxytocin. Am. J. Physiol. Endocrinol. Metab., 2006 Mar; 290(3):E566-72.